High quality SR9011 SARM bodybuilding supplement CAS 1379686-29-9
SR9011 is a potent and specific synthetic REV-ERB agonist, which can bind REV-ERB-α to EC50 of about 790 nM, and REV-ERB-β to ECV of about 560 nM. It also has good plasma/brain exposure in vivo. Nuclear receptors REV-ERB-α and REV-ERB-β play an indispensable role in regulating the expression of core clock proteins and instructing the rhythm of activity and metabolism.
Benefits of SR9011
SR9011 increases the metabolic rate of skeletal muscle and increases exercise endurance.
SR9011 promotes metabolism, fat burning and muscle growth
SR9009 VS SR9011
The difference between SR9009 and other weight-loss drugs is their chemical nature. Like many weight-loss drugs, SR9011 does not suppress appetite and can directly act by increasing muscle metabolism. Your metabolism naturally accelerates and slows down throughout the day, which means that sometimes food is used as energy and sometimes it is stored as fat. By resynchronizing the dysfunctional metabolic clock, SR9011 can ensure that food and excess fat are used as energy.
SR 9011 (Powder) Effects.
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure. Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.
Why do we need to use SARM ?
In general, SARMs offer three key benefits - increased muscle mass, decreased fat mass, and increased bone mass.
SARM aren’t just designed and meant for athletes; as previously discussed there are a slew of populations that could benefit from SARMs.
Those with one or more of the following conditions could benefit from SARMs: muscle wasting disorders (such as : sarcopenia, amyotrophic lateral sclerosis, and cystic fibrosis), sports injuries, burn injuries, weakness and/or body wasting due to cancer or HIV, and frailty and/or muscle atrophy as a result of the aging process.
Although there are many drugs designed to improve the health of these populations, SARMs also have the unique benefit of being non-methylated and non-aromatized by the body, so they’re not toxic to the liver nor do they convert in to other active androgen or estrogen compounds. Liver toxicity and aromatization is a very serious concern when using pro-hormones and AASs. As you can see, SARMs benefit both chronically ill individuals as well healthy individuals looking to maximize quality of life.
Furthermore, SARM have demonstrated the ability to minimize or prevent muscle trophy when muscles were immobilized in casts. This is great news for athletes who work hard on the field and in the weight room to build muscle mass, strength, and power as SARM may positively impact the recovery process.
MOQ: 10 gram
Packing: Aluminum foil bag / customized
Payment Terms: Western Union / Money Gram / BTC / T/T / L/C
Mode of Transportation: By air or ship
Express: FedEx, UPS, DHL, TNT, EMS
Loading Port: Shanghai, China/ optional
Delivery Lead Time: Within 3 days