Clotrimazole cas23593-75-1

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Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor.Target: Antifungal; CYPClotrimazole (brand name Canesten or Lotrimin) is an antifungal medication commonly used in the treatment of fungal infections (of both humans and other animals) such as vaginal yeast infections, oral thrush, and ringworm. It is also used to treat athlete’s foot and jock itch.It is commonly available as an over-the-counter substance in various dosage forms, such as a cream, and also (especially in the case of ear infection) as a combination medicine. It is also available as a troche or throat lozenge (prescription only). For ear infection, it is often applied in liquid form, as ear drops.The antimycotic drug clotrimazole inhibits the function of the gastric H,K-ATPase in a manner similar to that observed for the Na,K-ATPase. Because of the high hydrophobicity of the compound, the interaction between clotrimazole and the ion pump occurs at the membrane domain in the apolar core of the membrane. The enzymatic activity was inhibited with a half-saturating concentration of 5.2 microM. Various partial reactions of the pump cycle were analyzed with the electrochromic styryl dye RH421 that has been widely used to study the transport mechanism of P-type ATPases.

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23593-75-1 Raw Material Clotrimazole Powder is a synthetic pyrrole antifungal agent, which can inhibit a variety of pathogenic fungi and has bactericidal effect at high concentration. Clotrimazole inhibits fungal ergosterol and other sterol biosynthesis by interfering with cytochrome P450 activity; damages fungal cell membrane and changes its permeability, resulting in leakage of important substances; it can also inhibit fungal triglyceride and phospholipid biosynthesis; Chemicalbook can also inhibit oxidation and peroxidase activity, resulting in excessive accumulation of peroxides in cells, resulting in fungal subcellular structure degeneration and necrosis. Clotrimazole has broad-spectrum antifungal activity, and has good antibacterial activity against dermatophytes, trichophyton, Aspergillus, coloring fungi, Cryptococcus and Candida, and also has certain antibacterial activity against Sporothrix schenckii, Bacillus dermatitis, Clostridium, histoplasmosis and so on.

Functions

1.Clotrimazole powder is Broad-spectrum antifungal drugs. For systemic fungal infection, but also for local fungal infection.

2.Antifungal agents for the treatmentof epidermal and deep.

Applications

23593-75-1 Raw Material Clotrimazole Powder is mainly used for medical .

Hebei minshang Biotechnology Co., Ltd.

has a registered capital of RMB 3 million yuan.

Our goal is to survive by quality and develop by credit.

In the past two years, our products have spread over more than 30 countries in the world, the U.S.A, the Netherlands, Poland, Canada, England, Italy, India, Columbia and so on.

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Product can be ordered from milligrams to tons.

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MOQ: 10 gram

Packing: Aluminum foil bag / customized

Payment Terms: Western Union / Money Gram / BTC / T/T / L/C

Mode of Transportation: By air or ship

Express: FedEx, UPS, DHL, TNT, EMS

Loading Port: Shanghai, China/ optional

Delivery Lead Time: Within 3 days